Health functionality
Asama Hop Extract
 About Hop |
 About |
| Hop is known as a raw material for beer and are indispensable for its unique bitterness and aroma. In addition, it also has the role of extending the shelf life of beer by antibacterial and preservative properties. It has a long history of being edible, and it has been used since around the 6th century BC. It has been used not only as an ingredient in beer, but also as an herb and medicine due to its rich bioactivity. | Xanthohumol is a flavonoid unique to hops and is a valuable component of about 0.1~0.7% in dried hops. We have already use hop extract for extending shelf life of foods. But in recent years, various physiological activities such as metabolic syndrome have been clarified, so we have developed an extract containing a high concentration of xanthohumol, Asama hop extract. |
Feature of Asama Hop Extract
・olive color powder with hop aroma and bitter taste
・poorly soluble in water and easily soluble in 50% ethanol
・contain 9% xanthohumol
Bioacivity of xanthohumol
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Effect on Obesity |
Effect on Vascular plaque formation |
Effect on Bone Disease |
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| XN inhibits the increase of body weight. reference：Miyata. et al. J Biol Chem. 2015 Aug 14;290(33):20565-79. |
XN inhibits the vascular plaque formation. reference：Prakash. et al. Mol Nutr Food Res. 2013 October ; 57(10): 1718-1728 |
XN inhibits the formation of osteoclasts and bone resorption. reference：Jing et al. Sci Rep. 2015 Dec 1;5:17605. |
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Effect on Dementia |
Effect on Stress |
Effect on Cancer |
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| Xanthohumol suppresses Aβ production and tau hyperphosphorylation in N2a/APP cells via APP processing. reference：Huang et. al. Front Pharmacol. 2018 Apr 4;9:199. |
Xanthohumol selectively binds to GABA receptors in neurons of the brain and enhances its binding response. | Xanthohumol has been shown to have a broad spectrum as a chemotherapeutic agent against cancer cells such as breast, colorectal, ovarian, and prostate cancers in vitro. |
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